In silico Screening of Violacein as an epidermal growth factor receptor inhibitor
نویسندگان
چکیده
EGFR is a key player in the signalling cascades of various kinds cancers and tyrosine kinase inhibitors block signalling. Natural products have long been used as candidates for therapy management cancer. Violacein, bacterial pigment, has known its numerous biological applications such antimicrobial, antileishmanial, antiviral, well antitumoral. Computational studies concluded that it may activity against like pancreatic cancer, thyroid colorectal endometrial cancer indicating potential application broad range anti-cancerous drug. This study aimed to perform molecular docking violacein with protein ascertain inhibitor property, which could lead development novel anti-cancer
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ژورنال
عنوان ژورنال: International Journal of Health & Allied Sciences
سال: 2022
ISSN: ['2278-344X', '2278-4292']
DOI: https://doi.org/10.55691/2278-344x.1007